The present invention is a ventilator system designed to meet the requirements of patients in acute respiratory distress. The servo-based adjustable proportional valve-based ventilator system discussed supports various ventilation modes such as continuous mandatory ventilation, assist control ventilation and spontaneous breathing supports that may be controlled by adjustable valves and machine parameters that can be monitored on the graphical user interface that specifically supports this device and its multiple features.
To provide a catheter which has a hybrid reinforcement structure by braiding and coiling, places a low burden on a blood vessel, has smooth reachability, and has sufficient pressing property as rigidity on the proximal side is enhanced. It is a composite catheter and is used for flushing the media to the targeted site in a lumen system of a patient's body. The hybrid-braided tube discussed here having multiple braiding patterns to ensure the flexibility and improve the structural stability of catheter tube with kink resistant and better torque transfer throughout the tube. There are different types of hybrid braid configurations with various inner lumens and out jackets materials as well as the modified surface for drug coating and hydrophilic coating adherence onto the catheter surface is introduced according to their intended use. Various shapes and braids are customised to fulfil specific requirement in medical applications
Auxetic structure, including three-dimensional Auxetic films and Stents, are disclosed and applied to maintain the luminal patency of the diseased in vivo tubular pathways and to support the tubular structures, such as oesophagus, other gastrointestinal tubes, bile ducts and pulmonary passageways. One such structure constructed in accordance with this invention comprises of a plurality of unit cells. Each unit cell comprises of four angulated squares connected in a way to create a hollow rhombus (diamond-shaped) space between them. One such unit cell comprises of eight vertices; where four vertices A, B, C and D are the vertical vertices which connect to the neighbouring unit cells. The other four vertices a, b, c and d are the horizontal vertices which link to the adjacent unit cells of the same orientation. The unit cells are connected in rows and columns, and the expansion of Auxetic structure leads to the expansion of the structure in both axes. The Auxetic structure configurations invented can also be used, with similar dimensions or significantly different dimensions, for other applications. The three-dimensional Auxetic film used to manufacture seamed Auxetic stents, whereas seamless fabrication of the Auxetic stent is also disclosed.
This invention relates to the stent device for the coronary artery of the human heart, which is used to treat coronary artery disease and prevent localised blood flow constriction in obstructed coronary artery. The present invention demonstrates negative Poisson’s ratio and comprises of a new Auxetic structure, which makes the mechanical properties of the stent anisotropic. Therefore, a good mechanical adhesion between stent and arterial wall can be achieved owing to the anisotropic nature of the Auxetic stent and arterial wall. This design of coronary stent has the capability to retain the coronary artery patency after it is expanded in both radial and longitudinal directions. The Auxetic structure stent of present invention constructed with the plurality of unit cells interconnected with horizontal and vertical edges to form hinges and struts of the coronary stent. The structure of single unit cell consists of hollow diamond along with four angulated squircles. The horizontal edges of the unit cells joined the unit cells in the horizontal direction whereas vertical edges joined the unit cells in the vertical direction, thus forming the array of unit cells in the radial and horizontal directions. A conventional fabrication technique such as CNC precise laser cutting technique and surface treatment methods were used to develop the present invention of coronary stent. Moreover, this invention of Auxetic coronary stent shows no foreshortening and elastic recoil once it is deployed and plastically deformed.
The present invention provides an Auxetic structure, including an Auxetic film and tubular stent for long bone fractures that is implanted into the medullary canal, where it spans the fracture site, providing stability and compression. The device is constructed from an Auxetic material and comprises of a plurality of unitcells. Each unitcell comprises of six triangles connected in such a manner that creates a hollow star (three-pointed) shape at the centre of each unitcell. The stars are connected through their vertices via flexible hinges creating a structure of rigid rotating triangles. An array/pattern is created by repeating the connection of unitcells in both vertical and horizontal directions. The Auxetic nature (materials with negative value of Poisson’s ratio) of the stent allows the expansion of the structure in both radial and longitudinal directions. The Auxetic system can be made from similar dimensions or a connection of different sized triangles to achieve a wide range of Poisson’s ratio values. The three-dimensional Auxetic film used to manufacture seamed Auxetic stents, whereas seamless fabrication of the Auxetic stent is also disclosed.
A bandage assembly for simultaneous wound healing and controlled drug delivery application, comprising three different components is presented here. The bandage assembly is made for topical wounds and is composed of an Auxetic polymeric film, a drug reservoir, and a mechanism which will control the pore size of the Auxetic film and hence the transdermal delivery of drug through the wound. The three components of the bandage assembly are arranged in laminar fashion, one atop the other, conjugated at the ends. The Auxetic polymer film is composed of rotating squares geometry and has a negative Poisson’s ratio. Linear expansion of the controlling mechanism will also cause expansion of the attached polymeric film in both vertical and horizontal directions. The structure that controls film expansion operates through a scissor-like mechanism. The length of the mechanism increases in linear (vertical) direction if contractile force is applied at one end (horizontally) of the structure, that is perpendicular to the direction of linear extension. Thus the degree of linear extension in one direction influences expansion of the film beneath as well as the change in size of the pores of the Auxetic film, and hence the rate at which drug is delivered to the site of the wound.
The invention is related to the skeletal plate systems for tubular and flat bones, which aligns and upholds bone portions of the fractured bone in a selected spatial assembly. The present invention relates to negative Poisson’s ratio and provides a fracture fixation device of Auxetic nature which aligns and sustains the bone fragments in order to impart appropriate assembly to accomplish bone healing. The device described herein provides better alignment of bone portions and helps promote healing due to its Auxetic nature. Skeletal plate fixation system comprises an Auxetic plate and screws designed to stabilize bone upon attachment. The Auxetic structure of the present invention aims to restore the fractured segments back to their original anatomical location through micro-motion. The Auxetic structure allows for efficient fixation because its negative Poisson’s ratio allows for micro-movement, thereby offering a stable fixation with relative stability rather than absolute stability and promoting bone healing without causing any damage to blood supply or osteo-necrosis.
A wound healing device that acts through controlled drug delivery and exudate uptake is presented here. The wound healing device is designed for use on topical wounds and primarily comprises of a laminate arrangement of components that function together to aid wound healing. Drug delivery to the wound is controlled through an internal assembly of an auxetic polymeric membrane connected to a lead screw mechanism that is electronically modulated. Since the extension of the auxetic membrane is electronically controlled, the opening of the pores in the membrane can limit the elution of drug through the film and hence the amount of drug that reaches the wound bed. The skin contacting polymeric surface of the device has been designed with several features that aid in exudate uptake in response to negative pressure applied to the polymeric membrane surface. This device therefore, is meant for long term use, as the need for multiple dressing changes is circumvented because of the dual features of controlled drug delivery and exudate removal through the treatment regimen.
A needle holder, also known as needle driver, is a surgical instrument, similar to a haemostat, used by doctors and surgeons to hold a suturing needle for closing wounds during suturing and surgical procedures. The parts of a simple needle holder are the jaws, the joint and the handles. Most needle holders also have a clamp mechanism that locks the needle in place, allowing the user to manoeuvre the needle through various tissues. The device is manufactured through conventional processes and machining techniques. But through last few stages, the dimensional accuracy and functional quality is given great consideration. A decisive quality test is the ability of the Needle Holder to effectively hold suturing thread when given tension, normally referred to as Thread Tension Test. This specific test is conventionally performed by hand, and therefore lot to lot inconsistencies in product dimensions and functionality are imminent. This invention is the design of an industrial automation system which not only speeds up the Thread Tension Test, but also ensures consistent test parameters for pass/fail labelling of Needle Holders. The design of this invention is based on principles of mechanical engineering, electronic circuits and components, control systems and computer programming.
The design of a ligament augmentation device is disclosed, this design implemented in ligament repair device can be used to augment the healing process of anterior cruciate ligament through primary repair. This device will not only be bioactive to help in the healing process of the ligament but also withstand the forces that act on the ligament during the motion of the knee. The design of the device is in a seamless tubular configuration and its geometry consists of multiple slit that are in inter-articular region and holes at both the ends of the device. Gates are located inside the tubular device, they seal off the ends of the device located in the bony tunnels from the part of the device that is to be fixed inside the knee joint. The feature of gates has been incorporated into the design of the device to allow the device to be fixed with bone cement. This document also discloses the fabrication methods used to produce ligament augmentation stent technology, LAST, a seamless tubular ligament augmentation device.
An expansion device for deployment of auxetic stents, comprising of multiple parts is presented here. The deployment device is designed specifically for expansion of auxetic stents and is composed of circular rods and spokes. The length of spokes and rods will control the extent of elongation both radially and longitudinally. All the parts of the deployment device are arranged in order to obtain umbrella shaped geometry connected end to end. The Auxetic polymeric stent is composed of rotating square geometry having negative Poisson’s ratio. The device is actuated through hydraulic pressure applied by inflation device. The device and the stent expansion operates through an umbrella like mechanism. The length of auxetic stent increases when external pressure is applied. The spokes are expanded in response to pressure thus expanding the stent radially. The degree of linear expansion in one direction influences expansion of auxetic stent in other direction as well. As the device exerts pressure longitudinally, the force is applied on more unit cells/hinges which results in overall expansion of auxetic stent.